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CAS RN: 745-65-3 | Product Number: P1917
Prostaglandin E1
Purity: >98.0%(HPLC)
Synonyms:
- Alprostadil
- PGE1
- (11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-13-en-1-oic Acid
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | P1917 |
Purity / Analysis Method | >98.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__0H__3__4O__5 = 354.49 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (-20°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 745-65-3 |
Reaxys Registry Number | 2061617 |
PubChem Substance ID | 468592574 |
Merck Index (14) | 7875 |
MDL Number | MFCD00077860 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Melting point | 115.0 to 119.0 °C |
Specific rotation | -64.0 to -68.0 deg(C=0.2,ethanol) |
NMR | confirm to structure |
Properties (reference)
Melting Point | 116 °C |
Maximum Absorption Wavelength | 278(EtOH) nm |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H301 : Toxic if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
RTECS# | GY4569800 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | III |
H.S.code* | 2937.50-000 |
Application
Prostaglandin E1: A Naturally Occurring Prostaglandin with Vasodilation and Anti-Platelet Aggregating Effects
Prostaglandin E1 (PGE1) is produced by the theoretical metabolism of dihomo-y-linolenic acid (DGLA) [E0640] by the cyclooxygenase pathway.1) It has been reported that PGE1 has many pharmacological activities, such as vasodilation, anti-inflammatory, anti-platelet aggregation, protection of vascular endothelial cells, prevention of atherosclerosis, and so on.2) PGE1 is known to improve fluidity of blood through its vasodilation and anti-platelet aggregating effects. (The product is for research purpose only.)
References
- 1) Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunction
- 2) The rationale for prostaglandin E1 in erectile failure: A survey of worldwide experience (a review)
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