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CAS RN: 144689-63-4 | Product Number: O0510
Olmesartan Medoxomil
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩144,300
|
2 | 0 | Contact Us | |
| 5G |
₩495,800
|
8 | 7 | Contact Us |
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | O0510 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__9H__3__0N__6O__6 = 558.60 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 144689-63-4 |
| Reaxys Registry Number | 7506931 |
| PubChem Substance ID | 354335790 |
| Merck Index (14) | 6839 |
| MDL Number | MFCD00944911 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 180 °C(dec.) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Methanol, Acetone |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | NI4014200 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Olmesartan Medoxomil: A Prodrug of Olmesartan, a Selective AT1 Subtype Angiotensin II Receptor Antagonist
Olmesartan medoxomil (CS-866), a prodrug, is hydrolyzed to the active metabolite olmesartan [O0507] during absorption from the gastrointestinal tract. Olmesartan is a selective AT1 subtype angiotensin II receptor antagonist (“sartan”). Olmesartan medoxomil is used for the treatment of hypertension. (The product is for research purpose only.)
References
- Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist
- Real-time monitoring of metabolic reactions by microdialysis in combination with tandem mass spectrometry: hydrolysis of CS-866 in vitro in human and rat plasma, livers, and small intestines
- Hydrolysis of angiotensin II receptor blocker prodrug olmesartan medoxomil by human serum albumin and identification of its catalytic active sites
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