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CAS RN: 475-83-2 | Product Number: N1170
Nuciferine
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Purity: >97.0%(GC)
Synonyms:
- 1,2-Dimethoxy-6αβ-aporphine
- (R)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
₩1,108,200
|
11 | 10 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | N1170 |
| Purity / Analysis Method | >97.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__9H__2__1NO__2 = 295.38 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 475-83-2 |
| Reaxys Registry Number | 91202 |
| PubChem Substance ID | 468592496 |
| MDL Number | MFCD01664592 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(GC) | min. 97.0 % |
| Specific rotation | -148 to -155 deg(C=0.5, EtOH) |
Properties (reference)
| Melting Point | 166 °C |
| Specific Rotation | -152° (C=0.5,EtOH) |
| Maximum Absorption Wavelength | 270(H2O) nm |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | CE0350000 |
Transport Information:
| UN Number | UN1544 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2939.79-000 |
Application
Nuciferine: An Aporphine Alkaloid with Several Pharmacological Activities
Nuciferine is an aporphine alkaloid contained in lotus leaves (N. nucifera Gaertn), which is a raw material in Chinese medicinal herb for weight loss. Nuciferine has been reported to possess several pharmacological activities, including insulin secretagogue,1) anti-cancer,2,3) anti-hyperlipidemia4) and anti-inflammatory4) activities. (The product is for research purpose only.)
References
- 1) Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide
- 2) Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer
- 3) Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach
- 4) Nuciferine restores potassium oxonate-induced hyperuricemia and kidney inflammation in mice
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