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CAS RN: 3575-80-2 | Product Number: M2622
Melperone
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Purity: >95.0%(GC)
Synonyms:
- 4'-Fluoro-4-(4-methylpiperidino)butyrophenone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
₩131,400
|
7 | 0 | Contact Us | |
| 100MG |
₩386,700
|
8 | 9 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | M2622 |
| Purity / Analysis Method | >95.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__6H__2__2FNO = 263.36 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 3575-80-2 |
| Reaxys Registry Number | 1379151 |
| PubChem Substance ID | 253662483 |
| Merck Index (14) | 5827 |
| MDL Number | MFCD00867737 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 78.0 to 82.0 °C |
Properties (reference)
| Melting Point | 80 °C |
| Boiling Point | 125 °C/0.1 mmHg |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Melperone: A 5-HT2A/D2 Receptor Antagonist
Melperone is a 5-HT2A/D2 receptor antagonist, and also binds adrenergic α1 and α2 receptors. Meanwhile, melperone works as an inhibitor of CYP2D6. Melperone is used as an atypical neuroleptic. Melperone is structurally related to the typical antipsychotic haloperidol [H0912]. (The product is for research purpose only.)
References
- Melperone and clozapine: neuroendocrine effects of atypical neuroleptic drugs (a review)
- Pharmacological data of the atypical neuroleptic compound melperone (Buronilr̀) (a review)
- Binding of antipsychotic drugs to human brain receptors - focus on newer generation compounds
- Melperone in the treatment of neuroleptic-resistant schizophrenia
- P-glycoprotein is a factor in the uptake of dextromethorphan, but not of melperone, into the mouse brain: evidence for an overlap in substrate specificity between P-gp and CYP2D6
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