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CAS RN: 152459-95-5 | Product Number: I0906
Imatinib
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Purity: >98.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
₩92,500
|
0 | 22 | It can be shipped in about 2 weeks after ordering | |
| 1G |
₩555,000
|
1 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | I0906 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__9H__3__1N__7O = 493.62 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 152459-95-5 |
| Related CAS RN | 220127-57-1 |
| Reaxys Registry Number | 9300263 |
| PubChem Substance ID | 253661909 |
| Merck Index (14) | 4902 |
| MDL Number | MFCD05662257 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 97.0 % |
| Melting point | 207.0 to 211.0 °C |
Properties (reference)
| Melting Point | 209 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | CV5585673 |
Transport Information:
| H.S.code* | 2933.59-000 |
Application
Imatinib: A Tyrosine Kinase Inhibitor and a Molecular-Targeted Agent
Imatinib is a synthetic tyrosine (Tyr) kinase inhibitor and a molecular-targeted agent that specifically target several protein tyrosine kinases, such as stem-cell factor receptor (c-KIT), platelet-derived growth factor receptor (PDGF-R), and notably Bcr-Abl. Imatinib mesylate [I0936] is used in the treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies. (The product is for research purpose only.)
References
- Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
- Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug (a review)
- Mechanisms and implications of imatinib resistance mutations in BCR-ABL (a review)
- The development of imatinib as a therapeutic agent for chronic myeloid leukemia
- Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukemia
PubMed Literature
Articles/Brochures
TCIMAIL
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Safety Data Sheet (SDS)
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Specifications
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