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CAS RN: 26807-65-8 | Product Number: I0730
Indapamide
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Purity: >97.0%(T)(HPLC)
Synonyms:
- 1-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩170,200
|
9 | 0 | It can be shipped in about 2 weeks after ordering | |
| 5G |
₩490,300
|
12 | 15 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | I0730 |
| Purity / Analysis Method | >97.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__6ClN__3O__3S = 365.83 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 26807-65-8 |
| Reaxys Registry Number | 1604026 |
| PubChem Substance ID | 87561081 |
| Merck Index (14) | 4935 |
| MDL Number | MFCD00079375 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 97.0 % |
| Melting point | 167.0 to 173.0 °C |
Properties (reference)
| Melting Point | 170 °C |
GHS
Related Laws:
| RTECS# | CV2451200 |
Transport Information:
| H.S.code* | 2935.90-000 |
Application
Indapamide: A Thiazide-Like Antihypertensive/Diuretic Agent
Indapamide is a thiazide-like antihypertensive/diuretic agent. Incidentally, thiazide diuretic agents include hydrochlorothiazide [H1274] and xipamide. Indapamide molecule contains both a polar sulfamoyl chlorobenzamide moiety and a lipid-soluble methylindoline moiety. Indapamide have a mild diuretic activity and a peripheral vasodilatory effect. The mechanism of action has not been completely elucidated, but indapamide affects the distal convoluted tubules, where they inhibit Na+/Cl- cotransport in the luminal membrane of tubule cells. Thus, reabsorption of NaCl and water is inhibited. (The product is for research purpose only.)
References
- Pharmacokinetics and metabolism of indapamide: a review
- The pharmacology and clinical pharmacology of indapamide
- Pharmacological properties of indapamide: rationale for use in hypertension (a review)
- Indapamide sustained release: a review of its use in treatment of hypertension (a review)
- Comparison of spectrophotometric and an LC method for the determination perindopril and indapamide in pharmaceutical formulations
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