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CAS RN: 54952-43-1 | Product Number: H1780
(±)-Shikonin
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Purity: >98.0%(HPLC)
Synonyms:
- (±)-Alkannin
- (±)-Shikalkin
- (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione
- (±)-5,8-Dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-1,4-naphthoquinone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
₩151,700
|
2 | 10 | It can be shipped in about 3-4 weeks after ordering | |
| 50MG |
₩505,100
|
7 | 0 | It can be shipped in about 3-4 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | H1780 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__6H__1__6O__5 = 288.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 54952-43-1 |
| PubChem Substance ID | 468592048 |
| MDL Number | MFCD00016668 |
Specifications
| Appearance | Orange to Brown powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 147.0 to 151.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 149 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2914.69-000 |
Application
A Crude Medicine Ingredients with Strong Anticancer Effects
Zicao, a traditional Chinese herbal medicine made from the dried root of Lithospermum erythrorhizon, has been used for the topical treatment of wounds in the form of oil-based ointment for several hundred years.1) The naphthoquinone (±)-shikonin is the main active substance of Zicao, and has been shown to possess many diverse properties including antioxidant, anti-inflammatory, antithrombotic, antimicrobial, and wound healing effects. In particular, many studies have demonstrated that shikonin exerts strong anticancer effects on various types of cancer by anti-angiogenesis, inhibiting cell proliferation and migration, inducing apoptosis, autophagy, and necroptosis.1-4) Shikonin also triggers Reactive Oxygen Species (ROS) generation, suppressing exosome release, and activate anti-tumor immunity in multiple molecular mechanisms.4) (The product is for research purpose only.)
References
- 1) Shikonin, an ingredient of Lithospermum erythrorhizon, inhibits angiogenesis in vivo and in vitro
- 2) Cellular pharmacology studies of shikonin derivatives (a review)
- 3) Pharmacological properties of shikonin - a review of literature since 2002 (a review)
- 4) Pharmacological properties and derivatives of shikonin-A review in recent years (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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