Maintenance Notice (3:15 - 7:30 AM February 22, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Notice of Discontinuing the Use of Password-Protected Compressed Files | Product Document Searching Made Easy by 2D Code! | TCI Life Science News February 2025 | [Product Highlights] Chemiluminescent Reagents for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 64-18-6 | Product Number: F0513
Formic Acid
×
![]()
×
Purity:
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 300ML |
₩37,000
|
23 | ≥100 | It can be shipped in about 2-3 business days after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | F0513 |
| Molecular Formula / Molecular Weight | CH__2O__2 = 46.03 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 64-18-6 |
| Reaxys Registry Number | 1209246 |
| Merck Index (14) | 4241 |
| MDL Number | MFCD00003297 |
Specifications
| Appearance | Colorless clear liquid |
| Concentration(Neutralization titration) | min. 88.0 w/w% |
Properties (reference)
| Melting Point | 8 °C |
| Boiling Point | 100 °C |
| Flash point | 57 °C |
| Specific Gravity (20/20) | 1.20 |
| Refractive Index | 1.37 |
| Solubility in water | Completely miscible |
| Solubility (miscible with) | Ethanol, Ether, Methanol |
| Solubility (soluble in) | Benzene, Toluene |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H331 : Toxic if inhaled. H302 : Harmful if swallowed. H314 : Causes severe skin burns and eye damage. H370 : Causes damage to organs. H373 : May cause damage to organs through prolonged or repeated exposure. H402 : Harmful to aquatic life. H226 : Flammable liquid and vapor. H290 : May be corrosive to metals. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P240 : Ground/bond container and receiving equipment. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P233 : Keep container tightly closed. P234 : Keep only in original container. P243 : Take precautionary measures against static discharge. P241 : Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 : Use only non-sparking tools. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P390 : Absorb spillage to prevent material damage. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P403 + P235 : Store in a well-ventilated place. Keep cool. P406 : Store in corrosive resistant container with a resistant inner liner. P405 : Store locked up. |
Related Laws:
| RTECS# | LQ4900000 |
Transport Information:
| UN Number | UN1779 |
| Class | 8 / 3 |
| Packing Group | II |
| H.S.code* | 2915.11-000 |
Application
Deprotection of Tr Groups using Formic Acid
Reference
- Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols
- P. G. M. Wuts, in Greene’s Protective Groups in Organic Synthesis, 5th ed., ed. by P. G. M. Wuts, John Wiley & Sons, Inc., Hoboken, New Jersey, 2014, Chap. 2, 17.
Application
Synthesis of Formamide Derivatives Catalyzed by Vitamin B1 Hydrochloride
N-Formination of aniline using VB1 as a catalyst:
A mixture of aniline (5 mmol), formic acid (1 mL), and VB1 (0.1 mmol, 2 mol%) is heated at 80 °C under stirring for 10 minutes. After completion of the reaction as indicated by TLC, 20 mL of EtOAc is added and washed with 5% HCl aq., 5% Na2CO3 aq., and brine. Then, the organic layer is dried over MgSO4 and concentrated to afford N-formylaniline in 96% yield without further purification.
A mixture of aniline (5 mmol), formic acid (1 mL), and VB1 (0.1 mmol, 2 mol%) is heated at 80 °C under stirring for 10 minutes. After completion of the reaction as indicated by TLC, 20 mL of EtOAc is added and washed with 5% HCl aq., 5% Na2CO3 aq., and brine. Then, the organic layer is dried over MgSO4 and concentrated to afford N-formylaniline in 96% yield without further purification.
References
- A convenient one-pot synthesis of formamide derivatives using thiamine hydrochloride as a novel catalyst
PubMed Literature
Articles/Brochures
TCIMAIL
[TCIMAIL No.160] Organic Syntheses Utilizing the Chemical Properties of Chlorosulfonyl Isocyanate[Product Highlights] Synthesis of Formamide Derivatives Catalyzed by Vitamin B1 Hydrochloride
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.
Other Documents
Related Products
![Formic Acid [for LC-MS]](/medias/F0654.jpg?context=bWFzdGVyfHJvb3R8MzAyMDF8aW1hZ2UvanBlZ3xhRFJqTDJnd09TODRPVE13TmpZeE16WTNPRE00TDBZd05qVTBMbXB3Wnd8YTEyOThhZGM1YzNmZTE3MTExYmM0NDM0ZjI5MmE1NDEwODNkZTI5Yzc4YTM1MTFiNDIxNmZlZDNhZWViZDdlYg "Formic Acid [for LC-MS]")
Formic Acid [for LC-MS]
| Product # | F0654 |
| CAS RN | 64-18-6 |
| Purity / Analysis Method: | >98.0%(GC) |