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CAS RN: 550-24-3 | Product Number: E1547
Embelin
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Purity: >95.0%(T)(HPLC)
Synonyms:
- Embelic Acid
- 2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
₩547,600
|
18 | 0 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | E1547 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__6O__4 = 294.39 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 550-24-3 |
| Reaxys Registry Number | 1885786 |
| MDL Number | MFCD00016369 |
Specifications
| Appearance | Light yellow to Yellow to Orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 95.0 % |
| Melting point | 143.0 to 147.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 145 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H413 : May cause long lasting harmful effects to aquatic life. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | DK4230000 |
Transport Information:
| H.S.code* | 2914.69-000 |
Application
Embelin: A Non-Peptidic XIAP Inhibitor
Embelin is a plant-based benzoquinone that is the major active constituent of the fruits of Embelia ribes Burm, which has been used as a traditional medicinal plant since time immemorial. There are reports that embelin is a non-peptide inhibitor of XIAP (the X-linked inhibitor of apoptosis protein), an anti-apoptotic protein. Embelin acts as a modulator of the NF-κB, p53, PI3K/AKT, and STAT3 signaling pathways. It also exhibits potent cytotoxic, antioxidant and cancer chemopreventive effects. Therefore, embelin inhibits cell growth and induces apoptosis in cancer cells. (The product is for research purpose only.)
References
- Discovery of Embelin as a Cell-Permeable, Small-Molecular Weight Inhibitor of XIAP through Structure-Based Computational Screening of a Traditional Herbal Medicine Three-Dimensional Structure Database
- Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-κB (NF-κB) signaling pathway leading to suppression of NF-κB-regulated antiapoptotic and metastatic gene products
- Free radical scavenging reactions and antioxidant activity of embelin: Biochemical and pulse radiolytic studies
- Embelin – a drug of antiquity: shifting the paradigm towards modern medicine (a review)
- The application of embelin for cancer prevention and therapy (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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