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CAS RN: 522-17-8 | Product Number: D5646
(-)-Deguelin
Purity: >95.0%(HPLC)
Synonyms:
- (7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-pyrano[2,3-c:6,5-f']dichromen-7(7aH)-one
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
50MG |
₩973,100
|
13 | 0 | Contact Us |
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sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | D5646 |
Purity / Analysis Method | >95.0%(HPLC) |
Molecular Formula / Molecular Weight | C__2__3H__2__2O__6 = 394.42 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Frozen (<0°C) |
Condition to Avoid | Heat Sensitive |
CAS RN | 522-17-8 |
Reaxys Registry Number | 1334183 |
PubChem Substance ID | 468591474 |
MDL Number | MFCD01740600 |
Specifications
Appearance | White to Yellow to Green powder to crystal |
Purity(HPLC) | min. 95.0 area% |
Specific rotation | -59.0 to -63.0 deg(C=1, methanol) |
NMR | confirm to structure |
Properties (reference)
Melting Point | 87 °C |
Maximum Absorption Wavelength | 314(MeOH) nm |
GHS
Related Laws:
RTECS# | DX1500000 |
Transport Information:
H.S.code* | 2932.99-000 |
Application
Deguelin: a naturally occurring rotenoid and an Akt inhibitor
Deguelin is a naturally occurring rotenoid of the flavonoid family contained in several plant species belonging to the legume family such as Derris trifoliata Lour, and has been used as a naturally occurring insecticide. In vitro and in vivo studies suggests that deguelin exerts potent anticancer activity against multiple cancer types and exhibits chemopreventive potential in Akt-inducible transgenic mouse models. (The product is for research purpose only.)
References
- Cancer chemopreventive activity mediated by deguelin, a naturally occurring rotenoid
- Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
- Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential (a review)
Product Documents (Note: Some products will not have analytical charts available.)
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