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CAS RN: 4143-62-8 | Product Number: D4794
3',4'-Dimethoxyflavone
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Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
₩131,400
|
4 | 1 | Contact Us | |
| 1G |
₩464,400
|
19 | 2 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | D4794 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__7H__1__4O__4 = 282.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 4143-62-8 |
| Reaxys Registry Number | 236749 |
| PubChem Substance ID | 354333484 |
| MDL Number | MFCD00143009 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 151.0 to 155.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 153 °C |
| Maximum Absorption Wavelength | 334(MeOH) nm |
GHS
Related Laws:
| RTECS# | DJ3012950 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
3',4'-Dimethoxyflavone: An Inhibitor of Poly (ADP-Ribose) Polymerase (PARP) Enzymes
Genomic instability is a hallmark of cancer and is often the result of altered DNA repair capabilities in tumor cells. Poly (ADP-ribose) polymerases (PARPs) are enzymes responsible for DNA damage detection and repair factor recruitment. PARP inhibitors are able to interact with the binding site for the PARP cofactor NAD+ and trap PARP on DNA, and induce cell death through replication stress-induced mitotic catastrophe. It has been reported that 3',4'-dimethoxyflavone is a PARP inhibitor and has neuroprotective effects. (The product is for research use only.)
Reference
- Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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