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CAS RN: 2265-92-1 | Product Number: D3594
1,4-Difluoro-2-iodobenzene
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Purity: >98.0%(GC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
₩40,700
|
11 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | D3594 |
| Purity / Analysis Method | >98.0%(GC) |
| Molecular Formula / Molecular Weight | C__6H__3F__2I = 239.99 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Condition to Avoid | Light Sensitive |
| CAS RN | 2265-92-1 |
| Reaxys Registry Number | 2081101 |
| PubChem Substance ID | 87559832 |
| MDL Number | MFCD03094151 |
Specifications
| Appearance | Colorless to Light yellow to Light red clear liquid |
| Purity(GC) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 183 °C |
| Flash point | 85 °C |
| Specific Gravity (20/20) | 2.01 |
| Refractive Index | 1.56 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H227 : Combustible liquid. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P210 : Keep away from heat/sparks/open flames/hot surfaces. No smoking. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P370 + P378 : In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P403 + P235 : Store in a well-ventilated place. Keep cool. |
Related Laws:
Transport Information:
| H.S.code* | 2903.99-000 |
Application
Dorsomorphin (Compound C): An Inhibitor of BMP Sinnaling and AMPK
Dorsomorphin (Compound C) is used as an inhibitor of bone morphogenetic protein (BMP) signaling, and an inhibitor of AMP-activated protein kinase (AMPK).
BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. Dorsomorphin inhibit the BMP signaling.
AMP-activated protein kinase (AMPK), a serine/threonine kinase, is an evolutionarily conserved energy sensor important for cell growth, proliferation, survival, and metabolic regulation. Dorsomorphin (Compound C) also inhibits the AMPK.
BMP plays a fundamental role in the regulation of bone organogenesis through the activation of receptor serine/threonine kinases, and BMP signaling regulates many different biological processes, including cell growth, differentiation, and embryogenesis. Dorsomorphin inhibit the BMP signaling.
AMP-activated protein kinase (AMPK), a serine/threonine kinase, is an evolutionarily conserved energy sensor important for cell growth, proliferation, survival, and metabolic regulation. Dorsomorphin (Compound C) also inhibits the AMPK.
References
- Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
- Small-molecule dissection of BMP signaling (a review)
- Compound C inhibits hypoxic activation of HIF-1 independent of AMPK
- Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway
- The AMPK Inhibitor Compound C Is a Potent AMPK-Independent Antiglioma Agent
PubMed Literature
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Safety Data Sheet (SDS)
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Specifications
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