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CAS RN: 70831-56-0 | Product Number: C3450
Chicoric Acid
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Purity: >98.0%(T)
Synonyms:
- (2R,3R)-2,3-Bis[[(E)-3-(3,4-dihydroxyphenyl)acryloyl]oxy]succinic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
₩161,000
|
6 | 1 | It can be shipped in about 2 weeks after ordering | |
| 50MG |
₩555,000
|
4 | 0 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | C3450 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__2__2H__1__8O__1__2 = 474.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 10MG-Glass Bottle with Plastic Insert (View image), 50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 70831-56-0 |
| Reaxys Registry Number | 3229636 |
| PubChem Substance ID | 354335030 |
| MDL Number | MFCD22683653 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 97.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -360 to -400 deg(C=1, MeOH) |
Properties (reference)
| Melting Point | 206 °C |
| Specific Rotation | -370° (C=1,MeOH) |
| Maximum Absorption Wavelength | 327 nm |
GHS
Related Laws:
| RTECS# | EJ9852090 |
Transport Information:
| H.S.code* | 2918.29-000 |
Application
Chicoric Acid: A Phenylpropanoid with a Variety of Biological Effects including Anti-HIV Activity
Chicoric acid is a phenylpropanoid found in a number of plants, such as chicory (Cichorium intybus) and Echinacea (Echinacea purpurea), and reportedly has a variety of biological functions, such as antioxidant, anti-inflammatory, antiviral and analgesic activities, and antihyperglycemic effect.1-3) Recently, chicoric acid and its analogs are attracting attention to their anti-HIV activity as HIV-1 integrase inhibitors.4,5) (The product is for research purpose only.)
References
- 1)Chicoric acid is an antioxidant molecule that stimulates AMP kinase pathway in L6 myotubes and extends lifespan in Caenorhabditis elegans
- 2)Effect of Chicoric Acid on Mast Cell-Mediated Allergic Inflammation in Vitro and in Vivo
- 3)Antihyperglycemic effect of a natural chicoric acid extract of chicory (Cichorium intybus L.): a comparative in vitro study with the effects of caffeic and ferulic acids
- 4)Chicoric Acid Analogs as HIV-1 Integrase Inhibitors
- 5)Chicoric acid and its analogues as an anti-HIV integrase agents (a review)
- 6)Pharmacokinetics, tissue distribution, and plasma protein binding study of chicoric acid by HPLC-MS/MS
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