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CAS RN: 61422-45-5 | Product Number: C2663
Carmofur
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 5-Fluoro-1-hexylcarbamoyluracil
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
₩201,700
|
3 | Contact Us |
| 5G |
₩630,900
|
6 | 22 |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | C2663 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__1H__1__6FN__3O__3 = 257.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 61422-45-5 |
| Reaxys Registry Number | 888898 |
| PubChem Substance ID | 160871373 |
| Merck Index (14) | 1844 |
| MDL Number | MFCD00866284 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 112 °C(dec.) |
| Solubility in water | Insoluble |
| Solubility (soluble in) | Chloroform, Acetone |
| Solubility (slightly sol. in) | Methanol, Ethanol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. H361 : Suspected of damaging fertility or the unborn child. H373 : May cause damage to organs through prolonged or repeated exposure. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | UV7714000 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| H.S.code* | 2933.59-000 |
Application
Carmofur (HCFU): 1-Hexylcarbamoyl Derivative of 5-FU
Carmofur (other name: HCFU) is an ester prodrug and metabolized by the action of CYP450 to form the active metabolite 5-FU [F0151].
References
- Antitumor activity of 1-hexylcarbamoyl-5-fluorouracil in a variety of experimental tumors
- Antitumor activity of 1-alkylcarbamoyl derivatives of 5-fluorouracil in a variety of mouse tumors
- Sensitivity of human KB cells expressing platelet-derived endothelial cell growth factor to pyrimidine antimetabolites
- Studies on the interaction between 1-hexylcarbamoyl-5-fluorouracil and bovine serum albumin
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