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CAS RN: 4291-63-8 | Product Number: C2499

Cladribine


Purity: >98.0%(HPLC)
Synonyms:
  • 2-Chloro-2'-deoxyadenosine
  • 2-Chloro-9-(2-deoxy-β-D-arabinofuranosyl)adenine
  • CdA
Product Documents:
50MG
₩312,700
13   28   It can be shipped in about 2 weeks after ordering
* Please contact our distributor of SEJIN CI Co., Ltd. if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:  sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.

Product Number C2499
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__0H__1__2ClN__5O__3 = 285.69 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
Packaging and Container 50MG-Glass Bottle with Plastic Insert (View image)
CAS RN 4291-63-8
Reaxys Registry Number 624220
PubChem Substance ID 160871152
Merck Index (14) 2337
MDL Number

MFCD00153939

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
Melting Point 220 °C
Maximum Absorption Wavelength 265(EtOH aq.) nm
GHS
Related Laws:
RTECS# AU7357560
Transport Information:
H.S.code* 2940.00-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Studies on Chronic Lymphocytic Leukemia Cells

References

  • Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria
    • D. Genini, S. Adachi, Q. Chao, D. W. Rose, C. J. Carrera, H. B. Cottam, D. A. Carson, L. M. Leoni, Blood 2000, 96, 3537.
  • Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-β-D-arabinosyl-2-fluoroadenine
    • L. E. Robertson, S. Chubb, R. E. Meyn, M. Story, R. Ford, W. N. Hittelman, W. Plunkett, Blood 1993, 81, 143.
  • Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes
    • D. A. Carson, D. B. Wasson, R. Taetle, A. Yu, Blood 1983, 62, 737.


PubMed Literature


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