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CAS RN: 1492-18-8 | Product Number: C2235
Calcium Folinate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Folinic Acid Calcium Salt
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
₩148,000
|
6 | 7 |
| 5G |
₩436,600
|
6 | ≥40 |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | C2235 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__1CaN__7O__7 = 511.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Hygroscopic |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1492-18-8 |
| Related CAS RN | 58-05-9&6035-45-6&2060570-47-8 |
| Reaxys Registry Number | 5723924 |
| PubChem Substance ID | 87560126 |
| MDL Number | MFCD00006704 |
Specifications
| Appearance | Light orange to Yellow to Green powder to crystaline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Chelometric Titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 17.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility in water | Soluble |
| Solubility (insoluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | MA0600500 |
Transport Information:
| H.S.code* | 2934.99-000 |
Application
Calcium folinate: a Pharmaceutical Adjuvant for Folate Antagonists and 5-Fluorouracil
Calcium folinate is used as to reduce the harmful effects of folate antagonists such as methotrexate [M1664]. Calcium folinate is also used in synergistic combination with 5-fluorouracil [F0151] to enhance of its antitumor effect.
References
- Folate supplementation and methotrexate treatment in rheumatoid arthritis: a review
- Effect of folic or folinic acid supplementation on methotrexate-associated safety and efficacy in inflammatory disease: a systematic review
- Enhancement of the antitumor effects of 5-fluorouracil by folinic acid
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