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CAS RN: 87269-87-2 | Product Number: B5344
Benzyl (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylate Hydrochloride
![Benzyl (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylate Hydrochloride No-Image](/medias/B5344.jpg?context=bWFzdGVyfHJvb3R8NDg1MjF8aW1hZ2UvanBlZ3xhRFUzTDJneU15ODRPVEl3TXpnek5EZzRNRE13TDBJMU16UTBMbXB3Wnd8M2Y0YTAyNWJhMmJmNjBhMDdhYzEwZjFkMDY1MTJhMGQxMGEyMWU5ODgwZWExNzExNjk0MDdjZWNhZmM2MGRlYQ)
Purity: >98.0%(T)(HPLC)
Synonyms:
- (S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylic Acid Benzyl Ester Hydrochloride
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | B5344 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__5H__1__9NO__2·HCl = 281.78 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 87269-87-2 |
Reaxys Registry Number | 3636474 |
PubChem Substance ID | 354334662 |
MDL Number | MFCD04974076 |
Specifications
Appearance | White to Orange to Green powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Argentometric Titration) | min. 98.0 % |
Specific rotation [a]20/D | -28.0 to -32.0 deg(C=1, DMSO) |
Properties (reference)
Melting Point | 181 °C |
Specific Rotation | -31° (C=1,DMSO) |
Solubility (soluble in) | Methanol |
GHS
Related Laws:
Transport Information:
H.S.code* | 2933.99-000 |
Application
A Synthetic Intermediate of Ramipril
This reagent is used for the synthesis of ramipril (Hoe 498) [CAS: 87333-19-5][R0219], an ACE inhibitor.
References
- Synthesis of unnatural amino acids: (S,S,S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid
- Synthesis of a highly active angiotensin converting enzyme inhibitor: 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2-azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498)
- Asymmetric synthesis of (S,S,S)-2-aza-bicyclo[3.3.0]octane-3-carboxylic acid benzyl ester. Formal synthesis of ramipril
PubMed Literature
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