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CAS RN: 603-50-9 | Product Number: B5066
Bisacodyl
Purity: >98.0%(T)(HPLC)
Synonyms:
- 4,4'-(2-Pyridylmethylene)bisphenol Diacetate
Product Documents:
Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time | Shipping Information |
---|---|---|---|---|---|
5G |
₩96,200
|
≥40 | 5 | Contact Us | |
25G |
₩312,700
|
16 | 3 | Contact Us |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | B5066 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__2H__1__9NO__4 = 361.40 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 603-50-9 |
Reaxys Registry Number | 323727 |
PubChem Substance ID | 354334116 |
Merck Index (14) | 1242 |
MDL Number | MFCD00038039 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Melting point | 132.0 to 136.0 °C |
NMR | confirm to structure |
Properties (reference)
Melting Point | 134 °C |
Maximum Absorption Wavelength | 220(MeOH) nm |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
RTECS# | SM8750000 |
Transport Information:
H.S.code* | 2933.39-000 |
Application
Bisacodyl: A Diphenylmethane Stimulant Laxative
Bisacodyl is used as a diphenylmethane stimulant laxative. Bisacodyl is hydrolyzed by intestinal brush border enzymes and colonic bacteria to form an active metabolite bis(p-hydroxyphenyl)-2-pyridylmethane that acts directly on the colonic mucosa to produce colonic peristalsis. (The product is for research purpose only.)
References
- Entacetylierung und Resorption von phenolischen Laxantien
- Bis-(p-hydroxyphenyl)-pyridyl-2-methane: The common laxative principle of Bisacodyl and sodium picosulfate.
- Aspects of the pharmacology of diphenylmethane laxatives (bisacodyl, oxyphenisatin and phenolphthalein derivatives) (a review)
- R. B. Sund, Norvegica Pharm. Acta 1983, 45, 125.
- Nitric oxide as a mediator of bisacodyl and phenolphthalein laxative action: induction of nitric oxide synthase
- High-performance liquid chromatographic determination of bisacodyl in pharmaceutical dosage forms marketed in Australia
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