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CAS RN: 60628-96-8 | Product Number: B4173
Bifonazole
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Purity: >98.0%(GC)(T)
Synonyms:
- 1-(α,4-Diphenylbenzyl)imidazole
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days |
|---|---|---|---|
| 1G |
₩79,600
|
1 | 17 |
| 5G |
₩181,300
|
5 | ≥40 |
* Please contact our distributor of SEJIN CI Co., Ltd.
if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:
sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
| Product Number | B4173 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__2__2H__1__8N__2 = 310.40 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 60628-96-8 |
| Reaxys Registry Number | 618427 |
| PubChem Substance ID | 253660017 |
| Merck Index (14) | 1213 |
| MDL Number | MFCD00865567 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 147.0 to 151.0 °C |
Properties (reference)
| Melting Point | 149 °C |
| Solubility (soluble in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | NI3517000 |
Transport Information:
| H.S.code* | 2933.29-000 |
Application
Studies of Antifungal Activity of Bifonazole
Bifonazole is a substituted imidazole antifungal agent, which possesses a broad spectrum of activity against dermatophytes (trichophyton, microsporum, and epidermophyton), yeasts (candida), and malassezia furfur. Bifonazole works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes.
References
- Structure of Microsomal Cytochrome P450 2B4 Complexed with the Antifungal Drug Bifonazole: insight into P450 conformational plasticity and membrane interaction
- Molecular design of two sterol 14α-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole
- Chiral Azole Derivatives. 4.Enantiomers of Bifonazole and Related Antifungal Agents: Synthesis, Configuration Assignment, and Biological Evaluation
- Antifungal relative inhibition factors: BAY 1-9139, bifonazole, butoconazole, isoconazole, itraconazole (R 51211), oxiconazole, Ro 14-4767/002, sulconazole, terconazole and vibunazole (BAY n-7133) compared
in vitro with nine established antifungal agents - Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses
- T. E. Lackner, S. P. Clissold, Drugs 1989, 38, 204.
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