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CAS RN: 151-73-5 | Product Number: B4110
Betamethasone 21-Phosphate Disodium Salt
Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
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* The storage conditions are subject to change without notice.
* The storage conditions are subject to change without notice.
Product Number | B4110 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__2H__2__8FNa__2O__8P = 516.41 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Hygroscopic |
CAS RN | 151-73-5 |
Related CAS RN | 360-63-4 |
Reaxys Registry Number | 9684703 |
PubChem Substance ID | 253661950 |
Merck Index (14) | 1180 |
MDL Number | MFCD00200361 |
Specifications
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
Specific rotation [a]20/D | +99.0 to +105.0 deg(C=1, H2O(calcd.on anh.substance)) |
Water | max. 10.0 % |
NMR | confirm to structure |
Properties (reference)
Specific Rotation | 102° (C=1,H2O) |
Solubility in water | Slightly soluble |
GHS
Pictogram | |
Signal Word | Warning |
Hazard Statements | H302 : Harmful if swallowed. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
RTECS# | TU4056500 |
Transport Information:
H.S.code* | 2937.29-000 |
Application
Betamethasone 21-Phosphate Disodium Salt: A Synthetic Water-Soluble Glucocorticoid
Betamethasone 21-phosphate disodium salt is a synthetic water-soluble glucocorticoid and works as a glucocorticoid receptor agonist. It shows immunosuppressive, antiallergic, antipruritic and anti-inflammatory effects in vivo. Recently, formulation of nanoparticles with betamethasone 21-phosphate disodium salt and its release profile has been studied.
References
- Anti-inflammatory effects of betamethasone phosphate, dexamethasone phosphate and indomethacin on rabbit ocular inflammation induced by bovine serum albumin
- Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit
- Treatment of experimental arthritis with poly(D,L-lactic/glycolic acid) nanoparticles encapsulating betamethasone sodium phosphate
- Treatment of experimental arthritis with stealth-type polymeric nanoparticles encapsulating betamethasone phosphate
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