text.skipToContent text.skipToNavigation

Maximum quantity allowed is 999

Please select the quantity

CAS RN: 88495-63-0 | Product Number: A2191

Artesunate


Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
5G
₩90,700
2   ≥60  Contact Us
25G
₩286,800
30   1   Contact Us
* Please contact our distributor of SEJIN CI Co., Ltd. if you would like to purchase TCI products. The above prices do not include freight cost, customs charge and other charges to the destination. SEJIN CI Co., Ltd. (Phone: 02-2655-2480 / email:  sales@sejinci.co.kr)
* The storage conditions are subject to change without notice.

Product Number A2191
Purity / Analysis Method >98.0%(T)(HPLC)
Molecular Formula / Molecular Weight C__1__9H__2__8O__8 = 384.43 
Physical State (20 deg.C) Solid
Storage Temperature Refrigerated (0-10°C)
Condition to Avoid Heat Sensitive
CAS RN 88495-63-0
Reaxys Registry Number 6003212
PubChem Substance ID 87560999
Merck Index (14) 818
MDL Number

MFCD00866204

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %
Melting point 132.0 to 137.0 °C
Specific rotation [a]20/D +4.5 to +6.5 deg(C=1, CH2Cl2)
Properties (reference)
Melting Point 133 °C
Specific Rotation 5.5° (C=1,CH2Cl2)
Solubility (soluble in) Methanol
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H302 : Harmful if swallowed.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
Related Laws:
Transport Information:
H.S.code* 2932.99-000
*This code is applied to the products when TCI exports from Japan and not for import in your country.
Application
Efflux pump inhibitor

References


Application
Artesunate: A Semi-Synthetic Derivative of Antimalaria Artemisinin

Artesunate is a semi-synthetic derivative of artemisinin [A2118] which is a biological active ingredient isolated from a traditional Chinese herbal medicine Artemisia annua. Artesunate is a prodrug that is rapidly converted to its active metabolite dihydroartemisinin [D3793]. Artesunate and its analogs have high efficacy against Plasmodium falciparum in the blood stages of the disease. The exact mechanism of action is still not clear, while the endoperoxide (O-O) subunit of the trioxane ring is critical for antimalarial activity. Several lines of evidence indicate that the O-O bond is easily broken by Fe2+, generating a number of reactive radicals oxidatively damage parasite. In addition, after 2000’s, the anti-tumor and antiviral activities of artesunate have been reported. (The product is for research purpose only.)

References


PubMed Literature


TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.

The requested SDS is not available.

Please Contact Us for more information.

Specifications
C of A & Other Certificates
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The product with the lot number searched for has been discontinued and no related documentation is available.

Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.

A sample C of A for this product is not available at this time.

Analytical Charts
Please enter Lot Number Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.

The requested analytical chart is not available. Sorry for the inconvenience.

The product with the lot number searched for has been discontinued and no related documentation is available.

Other Documents

Session Status
Your session will timeout in 10 minutes. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page. minute. You will be redirected to the HOME page after session timeout. Please click the button to continue session from the same page.

Your session has timed out. You will be redirected to the HOME page.