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CAS RN: 2182-14-1 | Product Number: V0193
Vindoline
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Purity: >98.0%(HPLC)(qNMR)
Synonyms:
- Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-Acetoxy-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
¥24,000
|
20 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | V0193 |
| Purity / Analysis Method | >98.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__5H__3__2N__2O__6 = 456.54 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 2182-14-1 |
| Reaxys Registry Number | 68801 |
| MDL Number | MFCD27991347 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(qNMR) | min. 98.0 % |
| Melting point | 162.0 to 166.0 °C |
| Specific rotation | -59.0 to -65.0 deg(C=1.5, methanol) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 164 °C |
GHS
Related Laws:
| RTECS# | CJ0120000 |
Transport Information:
Application
Vindoline: A Chemical Precursor of Antitumor Vinca Alkaloids
Vindoline is an alkaloid found in the leaves of Catharanthus roseus.1,2) Vindoline has been used as a chemical precursor of vincristine [V0129] and vinblastine, antitumor vinca alkaloids.3,4)
References
- 1) Screening of Catharanthus roseus secondary metabolites by high-performance liquid chromatography
- 2) Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast
- 3) Total Synthesis of Vinblastine, Vincristine, Related Natural Products, and Key Structural Analogues
- 4) Modifications on the basic skeletons of vinblastine and vincristine (a review)
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