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CAS RN: 175865-59-5 | Product Number: V0158
Valganciclovir Hydrochloride
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Purity: >98.0%(T)
Synonyms:
- L-Valine 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl Ester Monohydrochloride
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 250MG |
¥6,500
|
29 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 1G |
¥20,300
|
15 | 4 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | V0158 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__4H__2__2N__6O__5·HCl = 390.83 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 175865-59-5 |
| Reaxys Registry Number | 15558307 |
| PubChem Substance ID | 468593105 |
| Merck Index (14) | 9907 |
| MDL Number | MFCD08460118 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Argentometric Titration) | min. 98.0 %(calcd.on anh.substance) |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Water | max. 10.0 % |
Properties (reference)
| Solubility in water | Soluble |
| Solubility (soluble in) | Methanol, Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. H340 : May cause genetic defects. H351 : Suspected of causing cancer. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
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Transport Information:
Application
Valganciclovir Hydrochloride: An Oral Prodrug of Ganciclovir, with Enhanced Bioavailability
Valganciclovir is an oral prodrug of ganciclovir [G0315], with enhanced bioavailability than oral ganciclovir. After oral administration, valganciclovir is rapidly converted to ganciclovir by intestinal and hepatic esterases. The involvement of peptide transporter 1 (PEPT1) is indicated for the digestive absorption of valganciclovir.1,2) Ganciclovir is a synthetic analogue of 2’-deoxyguanosine with antiviral activity against members of the herpes group such as cytomegalovirus (CMV) and some other DNA viruses. Valganciclovir also interferes with herpes viral DNA synthesis and replication.3) (The product is for research purpose only.)
References
- 1) Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2
- 2) Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting
- 3) Valganciclovir (a review)
Articles/Brochures
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