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CAS RN: 36791-04-5 | Product Number: R0077
Ribavirin
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Purity: >98.0%(HPLC)(N)
Chemical Substance Law (ENCS):
9-1515
Synonyms:
- 1-(β-D-Ribofuranosyl)-1,2,4-triazole-3-carboxamide
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 100MG |
¥3,900
|
3 | 21 | ≥40 | |
| 500MG |
¥13,000
|
5 | 8 | ≥60 |
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | R0077 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__8H__1__2N__4O__5 = 244.21 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 36791-04-5 |
| Reaxys Registry Number | 892462 |
| PubChem Substance ID | 87559671 |
| Merck Index (14) | 8198 |
| MDL Number | MFCD00058564 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Specific rotation [a]20/D | -33.0 to -37.0 deg(C=1, H2O) |
Properties (reference)
| Specific Rotation | -36° (C=1,H2O) |
| Solubility in water | Soluble |
| Degree of solubility in water | 142 g/l 25 °C |
| Solubility (slightly sol. in) | Alcohol |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H360 : May damage fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| Chemical Substance Law (ENCS) |
9-1515 |
| RTECS# | XZ4250000 |
Transport Information:
Application
Ribavirin: A Ribonucleoside Analog with Antiviral Activity
Ribavirin, a ribonucleoside analog, shows antiviral activity against a variety of viruses both in vitro and in vivo. Although its mechanism of action remains unknown exactly, five distinct mechanisms have been proposed to explain the antiviral properties of ribavirin. These include both direct mechanisms (interference with RNA capping, RNA polymerase inhibition, lethal mutagenesis) and indirect mechanisms (inosine monophosphate dehydrogenase inhibition, immunomodulatory effects). Ribavirin is widely used in combination with interferon-α (IFN-α) to treat hepatitis C virus infection. The addition of ribavirin greatly improves IFN-α responses. (The product is for research purpose only.)
References
- The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
- RNA virus error catastrophe: direct molecular test by using ribavirin
- Mechanism of action of ribavirin in the combination treatment of chronic HCV infection (a review)
- Mechanism of action of interferon and ribavirin in treatment of hepatitis C (a review)
- Mechanisms of action of ribavirin against distinct viruses
- The metabolism, pharmacokinetics and mechanisms of antiviral activity of Ribavirin against hepatitis C virus (a review)
PubMed Literature
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Safety Data Sheet (SDS)
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Specifications
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