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CAS RN: 128-20-1 | Product Number: P3084

5β-Pregnan-3α-ol-20-one


Purity: >95.0%(HPLC)
Synonyms:
  • Pregnanolone
  • 3α-Hydroxy-5β-pregnan-20-one
  • 1-[(3R,5R,8R,9S,10S,13S,14S,17S)-3-Hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethan-1-one
Product Documents:
5MG
¥10,000
18   It can be shipped from Saitama warehouse on the same day* 31  
25MG
¥31,000
19   It can be shipped from Saitama warehouse on the same day* 25  
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Product Number P3084
Purity / Analysis Method >95.0%(HPLC)
Molecular Formula / Molecular Weight C__2__1H__3__4O__2 = 318.50 
Physical State (20 deg.C) Solid
Storage Temperature Room Temperature (Recommended in a cool and dark place, <15°C)
CAS RN 128-20-1
Reaxys Registry Number 3211364
MDL Number

MFCD00067137

Specifications
Appearance White to Light yellow powder to crystal
Purity(HPLC) min. 95.0 area%
Melting point 149.0 to 153.0 °C
Specific rotation +106 to +116 deg(C=1, ethanol)
NMR confirm to structure
Properties (reference)
Melting Point 151 °C
GHS
Pictogram Pictogram
Signal Word Warning
Hazard Statements H351 : Suspected of causing cancer.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P405 : Store locked up.
Related Laws:
RTECS# TU4384000
Transport Information:
Application
5β-Pregnan-3α-ol-20-one: An Endogenous Neuroactive Steroid

5β-Pregnan-3α-ol-20-one (or pregnanolone) and its stereoisomer, 3β-hydroxy-5α-pregnan-20-one [H1839], are metabolites of the ovarian/adrenal steroid progesterone [P0478].1) These metabolites are endogenous neuroactive steroids that act as a positive allosteric modulator (PAM) of γ-aminobutyric acid A (GABAA) receptors with anesthetic, anxiolytic, and anti-convulsant effects.2,3) (The product is for research purpose only.)

References


Product Documents (Note: Some products will not have analytical charts available.)
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