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CAS RN: 19666-76-3 | Product Number: P2811
Panaxadiol
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Purity: >95.0%(GC)
Synonyms:
- (3β,12β,20 R)-20,25-Epoxydammarane-3,12-diol
- (3S,5R,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-Pentamethyl-17-[(R)-2,6,6-trimethyltetrahydro-2H-pyran-2-yl]hexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 50MG |
¥13,000
|
1 | 9 | Contact Us | |
| 250MG |
¥45,500
|
20 | It can be shipped from Saitama warehouse on the same day* | 11 |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | P2811 |
| Purity / Analysis Method | >95.0%(GC) |
| Molecular Formula / Molecular Weight | C__3__0H__5__2O__3 = 460.74 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 250MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 19666-76-3 |
| Reaxys Registry Number | 6850005 |
| PubChem Substance ID | 468592734 |
| MDL Number | MFCD00210540 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(GC) | min. 95.0 % |
| Melting point | 245.0 to 249.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 247 °C |
GHS
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Transport Information:
Application
Panaxadiol: A Hydrolysate of Ginsenosides with a Wide Range of Pharmacological Effects
Ginsenosides can be isolated from from various plants, including Panax ginseng. However, the low membrane permeability and the gastrointestinal tract influence seriously limit the absorption and bioavailability of ginsenosides. Panaxadiol (another name: 20(R)-panaxadiol), a hydrolysate of ginsenosides, is expected to show improved bioavailability and diverse pharmacological activities. In fact, it has been reported that panaxadiol exerts a wide range of pharmacological effects including anticancer activity. Moreover, relative stable skeletons and active hydroxyl group at C-3 position and other reactive sites are suitable for structural modification to improve biological activities. (The product is for research purpose only.)
References
- Panaxadiol, a purified ginseng component, enhances the anti-cancer effects of 5-fluorouracil in human colorectal cancer cells
- The Synergistic Apoptotic Interaction of Panaxadiol and Epigallocatechin Gallate in Human Colorectal Cancer Cells
- Dammarane-type leads panaxadiol and protopanaxadiol for drug discovery: Biological activity and structural modification (a review)
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