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CAS RN: 31430-18-9 | Product Number: N1138
Nocodazole
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Purity: >98.0%(HPLC)
Synonyms:
- Methyl [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate
- [5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbamic Acid Methyl Ester
- Oncodazole
- R 17934
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
¥19,000
|
1 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 100MG |
¥55,000
|
17 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | N1138 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__1N__3O__3S = 301.32 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 100MG-Glass Bottle with Plastic Insert (View image), 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 31430-18-9 |
| Reaxys Registry Number | 1085978 |
| PubChem Substance ID | 468592478 |
Specifications
| Appearance | White to Orange to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 260 °C(dec.) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. H341 : Suspected of causing genetic defects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | DD6521000 |
Transport Information:
Application
CRISPR Genome Editing
The combination of cell cycle regulators, Nocodazole and CCND1 (cyclin D1), enhances CRISPR-mediated homology-directed repair (HDR) efficiency.1)
References
- 1) Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage
Application
Nocodazole: A Reversible Inhibitor of Polymerization of Microtubules
Nocodazole is a reversible inhibitor of polymerization of microtubules, and it binds with high affinity to tubulin and to inhibit microtubule assembly. Nocodazole has long been used as an experimental tool in cell biology.
References
- Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor nocodazole. Nocodazole accumulated mitotic cells
- Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles: implications for the role of microtubule dynamics in mitosis
- Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
- GEF-H1 couples nocodazole-induced microtubule disassembly to cell contractility via RhoA
Articles/Brochures
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Safety Data Sheet (SDS)
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Specifications
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