Maximum quantity allowed is 999
Please select the quantity
CAS RN: 62013-04-1 | Product Number: D5495
Dirithromycin
×
![]()
×
Purity: >98.0%(HPLC)(N)
Synonyms:
- [9S(R)]-9-Deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]erythromycin
- LY-237216
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥22,000
|
16 | 10 | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D5495 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__4__2H__7__8N__2O__1__4 = 835.09 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 62013-04-1 |
| Reaxys Registry Number | 6842524 |
| PubChem Substance ID | 468591372 |
| Merck Index (14) | 3354 |
| MDL Number | MFCD00865041 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 186.0 to 190.0 °C |
| Specific rotation [a]20/D | -85.0 to -90.0 deg(C=1, MeOH) |
Properties (reference)
| Melting Point | 188 °C |
| Specific Rotation | -88° (C=1,MeOH) |
GHS
Related Laws:
| RTECS# | JG5806477 |
Transport Information:
Application
Dirithromycin: A Macrolide Antibiotic with Outstanding Activity against Campylobacter
Dirithromycin is a macrolide antibiotic derived from erythromycin [E0751]. Dirithromycin is a prodrug, and is hydrolyzed in vivo to its major active metabolite, erythromycilamine.1) Although the antimicrobial spectrum of dirithromycin is similar to that of erythromycin, it reportedly has outstanding activity against Campylobacter.2) In addition, erythromycin inhibits cytochrome P450 isoform 3A4 (CYP3A4), but dirithromycin and azithromycin [A2076] neither inhibit CYP3A4 nor are implicated in clinically significant drug-drug interactions.3) (The product is for research purpose only.)
References
- 1) Synthesis and antimicrobial evaluation of dirithromycin (ASE 136; LY237216), a new macrolide antibiotic derived from erythromycin
- 2) Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides
- 3) Macrolide-induced clinically relevant drug interactions with cytochrome P-450A (CYP) 3A4: an update focused on clarithromycin, azithromycin and dirithromycin (a review)
- 4) Analysis of macrolide antibiotics (a review)
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.