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CAS RN: 141625-93-6 | Product Number: D4689
Dronedarone Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- N-[2-Butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]methanesulfonamide Hydrochloride
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
¥6,300
|
2 | It can be shipped from Saitama warehouse on the same day* | Contact Us | |
| 1G |
¥21,300
|
23 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | D4689 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__3__1H__4__4N__2O__5S·HCl = 593.22 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 141625-93-6 |
| Related CAS RN | 141626-36-0 |
| Reaxys Registry Number | 8380427 |
| PubChem Substance ID | 253660640 |
| Merck Index (14) | 3449 |
| MDL Number | MFCD00914940 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 142.0 to 146.0 °C |
Properties (reference)
| Melting Point | 144 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
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Application
Dronedarone Hydrochloride: A Non-Iodinated Benzofurane Derivative Antiarrhythmic Agent
Dronedarone hydrochloride, an antiarrhythmic agent, is a non-iodinated benzofurane derivative that has been developed to overcome the iodine-associated adverse effects of the structurally related antiarrhythmic agent, amiodarone [A2530]. Although it is considered a class III antiarrhythmic agent like amiodarone, it demonstrates multi-class electrophysiological activity. (The product is for research purpose only.)
References
- Electrophysiological effects of dronedarone (SR33589), a noniodinated benzofuran derivative, in the rabbit heart: comparison with amiodarone
- Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone
- Electrophysiologic Characterization of Dronedarone in Guinea Pig Ventricular Cells
- The novel antiarrhythmic drug dronedarone: Comparison with amiodarone (a review)
- RP-HPLC method development and validation of Dronedarone HCl in its pure form and tablet dosage form
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