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CAS RN: 288383-20-0 | Product Number: C3918
Cediranib
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Purity: >95.0%(T)(HPLC)
Synonyms:
- AZD 2171
- 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
¥10,000
|
37 | It can be shipped from Saitama warehouse on the same day* | Contact Us |
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*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | C3918 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__2__7FN__4O__3 = 450.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 288383-20-0 |
| Reaxys Registry Number | 11404252 |
| MDL Number | MFCD09954115 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
| Maximum Absorption Wavelength | 530(MeOH) nm |
GHS
Related Laws:
| RTECS# | VA1424500 |
Transport Information:
Application
Cediranib: A VEGF Receptor Tyrosine Kinase Inhibitor
Receptors for VEGF (vascular endothelial growth factor-A) play a central role in vasculogenesis and angiogenesis and are therefore targets for cancer therapy. Cediranib (AZD2171) and its water-soluble maleate [R0277] are VEGF receptor tyrosine kinase inhibitors used in cancer research. (The product is for research use only.)
References
- AZD2171 : A highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer
- The tyrosine kinase inhibitor cediranib for non-small cell lung cancer and other thoracic malignancies (a review)
- Cediranib , a pan-VEGFR inhibitor, and olaparib, a PARP inhibitor, in combination therapy for high grade serous ovarian cancer
- Solubility and stability of cediranib maleate
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Specifications
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