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CAS RN: 91702-98-6 | Product Number: A2220
2-[(Acetylthio)methyl]-3-phenylpropionic Acid
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![2-[(Acetylthio)methyl]-3-phenylpropionic Acid](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "2-[(Acetylthio)methyl]-3-phenylpropionic Acid")
Purity: >98.0%(T)
Synonyms:
Product Documents:
| Size | Unit Price | Saitama (Kawaguchi) | Hyogo (Amagasaki) | Stock in other WH |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
¥1,900
|
2 | It can be shipped from Saitama warehouse on the same day* | It can be shipped in about 4-5 weeks after ordering | |
| 5G |
¥5,800
|
8 | 4 | It can be shipped in about 4-5 weeks after ordering |
* Available Stock: Prompt shipment (for products) in Saitama/Hyogo warehouse. Stock In Other WH: Shipment in about 2-3 Business Days from Saitama warehouse. Please contact us
if you need further information.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
* The displayed price is the unit price and does not include consumption tax. The unit prices displayed are the latest and are subject to change without notice.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quote" button. Please note that we cannot offer bulk quantities for some products.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | A2220 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__2H__1__4O__3S = 238.30 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 91702-98-6 |
| Reaxys Registry Number | 4906822 |
| PubChem Substance ID | 87561563 |
| MDL Number | MFCD00236751 |
Specifications
| Appearance | White or Colorless to Yellow powder to lump to clear liquid |
| Purity(GC) | min. 93.0 % |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 39 °C |
| Refractive Index | 1.55 |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
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Application
A Synthetic Intermediate of Enkephalinase Inhibitors
This product has been used as a synthetic intermediate of enkephalinase inhibitors, such as racecadotril [R0103]. Enkephalinase is an enzyme that break down the endogenous enkephalin opioid peptides. In clinical, racecadotril is used in the treatment of acute diarrhea.
References
- Synthesis and pharmacological properties of 2-[S-acetylthiorphan]-1,3-diacylaminopropan-2-ol derivatives as chimeric lipid drug carriers containing an enkephalinase inhibitor
- Importance of the amide bond of thiorphan in the inhibitor-enkephalinase docking process demonstrated with some thiorphan isosteres
PubMed Literature
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Specifications
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