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CAS RN: 138489-18-6 | Product Number: R0257
Ro 31-8220 Mesylate

Purity: >98.0%(T)(HPLC)
- Bisindolylmaleimide IX
- 3-[3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl Carbamimidothioate Methanesulfonate
Size | Unit Price | Hyderabad | Japan* | Quantity |
---|---|---|---|---|
10MG |
₹16,500.00
|
Contact Us | ≥40 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | R0257 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__2__5H__2__3N__5O__2S·CH__4O__3S = 553.65 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Refrigerated (0-10°C) |
Store Under Inert Gas | Store under inert gas |
Condition to Avoid | Light Sensitive,Air Sensitive,Hygroscopic,Heat Sensitive |
CAS RN | 138489-18-6 |
Reaxys Registry Number | 5373685 |
MDL Number | MFCD03788207 |
Appearance | Orange to Red powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Volumetric Analysis) | min. 98.0 % |
Melting point | 237.0 to 241.0 °C |
NMR | confirm to structure |
Melting Point | 239 °C |
RTECS# | FD3070500 |
References
- 1) Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C
- 2) Protein kinase C in the treatment of disease: signal transduction pathways, inhibitors, and agents in development (a review)
- 3) The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220) are potent inhibitors of glycogen synthase kinase-3 activity
- 4) Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
- 5) Investigation of leucine-rich repeat kinase 2: Enzymological properties and novel assays
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