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CAS RN: 189224-26-8 | Product Number: O0660
Ozagrel Sodium
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Sodium Ozagrel
- Sodium (E)-3-[4-[(1H-Imidazol-1-yl)methyl]phenyl]acrylate
- Sodium (2E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]acrylate
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
₹2,400.00
|
Contact Us | 31 |
|
| 5G |
₹7,500.00
|
Contact Us | 26 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | O0660 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__1N__2NaO__2 = 250.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 189224-26-8 |
| MDL Number | MFCD00875845 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Solubility (soluble in) | Methanol |
| Solubility (insoluble in) | Ethanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H371 : May cause damage to organs. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P260 : Do not breathe dust. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P308 + P311 : IF exposed or concerned: Call a POISON CENTER/doctor. P405 : Store locked up. |
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Application
Ozagrel Sodium: A Selective Thromboxane A2 (TXA2) Synthetase Inhibitor
Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets during hemostasis and is also a potent constrictor of smooth muscle. Ozagrel sodium is a selective TXA2 synthetase inhibitor and blocks platelet aggregation and reduces bronchial muscle hypersensitivity. In clinical, it has been used as a therapeutic agent for ischemic heart diseases, thromboembolic disorders, cerebral circulatory disorders and asthma. (The product is for research purpose only.)
References
- Pharmacological studies on the TXA synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046)
- Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets
- Thromboxane A2 inhibition: Therapeutic potential in bronchial asthma (a review)
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