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CAS RN: 7729-94-4 | Product Number: N1171
Norlidocaine Hydrochloride
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Purity: >98.0%(T)(HPLC)
Synonyms:
- Monoethylglycinexylidide Hydrochloride
- N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide Hydrochloride
Product Documents:
| Size | Unit Price | Hyderabad | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
₹5,900.00
|
Contact Us | 23 |
|
| 100MG |
₹18,500.00
|
Contact Us | 24 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
| Product Number | N1171 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__2H__1__8N__2O·HCl = 242.75 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 7729-94-4 |
| Reaxys Registry Number | 3727115 |
| PubChem Substance ID | 468592497 |
| MDL Number | MFCD21334173 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 292 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
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Application
Norlidocaine (monoethylglycinexylidide: MEGX): A Main Active Metabolite of Lidocaine
Norlidocaine (monoethylglycinexylidide: MEGX) is a main active metabolite of lidocaine [L0156] formed by oxidative N-deethylation catalyzed by CYP1A2 and CYP3A4 in the liver, and its formation depends on liver microsomal activity. Therefore, the dynamic liver function test based on the hepatic conversion of lidocaine to MEGX (called MEGX test) has been used as a tool for the real-time assessment of hepatic function. (The product is for research purpose only.)
References
- Involvement of CYP1A2 and CYP3A4 in lidocaine N-deethylation and 3-hydroxylation in humans
- The MEGX test: a tool for the real-time assessment of hepatic function (a review)
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