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CAS RN: 3094-09-5 | Product Number: D3579
5'-Deoxy-5-fluorouridine
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Purity: >98.0%(T)(HPLC)
- 5'-dFUrd
- Doxifluridine
- 1-(5-Deoxy-β-D-ribofuranosyl)-5-fluorouracil
Size | Unit Price | Hyderabad | Japan* | Quantity |
---|---|---|---|---|
1G |
₹8,200.00
|
4 | ≥60 |
|
5G |
₹9,800.00
|
1 | ≥100 |
|
*Upon orders receipt, Hyderabad stocks will be dispatched on the same day.
*Items available in Japan warehouse will be dispatched in 10-12 working days.
*INR price is exclusive of domestic taxes applicable.
*TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.
Product Number | D3579 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__9H__1__1FN__2O__5 = 246.19 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 3094-09-5 |
Reaxys Registry Number | 890191 |
PubChem Substance ID | 87559877 |
Merck Index (14) | 3437 |
MDL Number | MFCD00866530 |
Appearance | White to Almost white powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 189.0 to 193.0 °C |
Specific rotation [a]20/D | +18.0 to +22.0 deg(C=1, H2O) |
Melting Point | 189 °C |
Specific Rotation | 20° (C=1,H2O) |
Pictogram |
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Signal Word | Warning |
Hazard Statements | H373 : May cause damage to organs through prolonged or repeated exposure. H317 : May cause an allergic skin reaction. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P272 : Contaminated work clothing should not be allowed out of the workplace. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P314 : Get medical advice/ attention if you feel unwell. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
RTECS# | YU7526000 |
References
- Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5'-deoxy-5-fluorouridine
- Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentrated in human liver and cancer tissue
- Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts
- Induction of thymidine phosphorylase expression and enhancement of efficacy of capecitabine or 5'-deoxy-5-fluorouridine by cyclophosphamide in mammary tumor models
- Thymidine phosphorylase and fluoropyrimidines efficacy: a Jekyl and Hyde story (a review)
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