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CAS RN: 1501-84-4 | Product Number: R0070
1-(1-Adamantyl)ethylamine Hydrochloride
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Purity: >98.0%(N)(NMR)
Synonyms:
- α-Methyl-1-adamantanemethylamine Hydrochloride
- Rimantadine Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
€67.00
|
2 | 9 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | R0070 |
| Purity / Analysis Method | >98.0%(N)(NMR) |
| Molecular Formula / Molecular Weight | C__1__2H__2__1N·HCl = 215.77 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 1501-84-4 |
| Related CAS RN | 13392-28-4 |
| Reaxys Registry Number | 3623918 |
| PubChem Substance ID | 87575628 |
| Merck Index (14) | 8224 |
| MDL Number | MFCD00072023 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Purity(qNMR) | min. 98.0 % |
| Solubility in hot Water | almost transparency |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 375 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| RTECS# | AU4717000 |
Transport Information:
| HS Number | 2921309990 |
Application
Rimantadine Hydrochloride: An Anti-Influenza A Virus Agent and a Dopamine Receptor Agonist
Rimantadine hydrochloride is an anti-influenza A virus agent and a dopamine receptor agonist, similarly amantadine hydrochloride [A0588]. Genetic studies suggest that rimantadine inhibits the replication of influenza A viruses by preventing the release of infectious viral RNA into the host cell nucleus by interfering with the function of the transmembrane of the viral M2 protein. In addition, there is evidence to suggest that rimantadine act as a dopamine receptor agonist. (The product is for research purpose only.)
References
- Structure and mechanism of the M2 proton channel of influenza A virus
- Mechanism of drug inhibition and drug resistance of influenza A M2 channel
- Comparison of neuronal responses to amantadine and rimantadine: use of α-flupenthixol
- Validation of a Capillary Zone Electrophoresis Method for Determination of Rimantadine Hydrochloride in Rimantadin100 Tablets and the Method Application to Dissolution Test Monitoring
- Determination of amantadine and rimantadine using a sensitive fluorescent probe
- Determination of rimantadine in human urine by HPLC using a monolithic stationary phase and on-line post-column derivatization
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