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Published TCIMAIL newest issue No.197
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CAS RN: 180272-45-1 | Product Number: P2215
(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
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Purity: >98.0%(GC)(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€142.00
|
Contact Us | 27 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | P2215 |
| Purity / Analysis Method | >98.0%(GC)(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__5N = 209.29 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 180272-45-1 |
| Reaxys Registry Number | 7794832 |
| PubChem Substance ID | 468592582 |
| MDL Number | MFCD11858641 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Optical purity(GC) | min. 98.0 ee% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | gt. 80.0 to 84.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 83 °C |
GHS
Related Laws:
Transport Information:
| HS Number | 2933499090 |
Application
A Key Synthetic Intermediate of Solifenacin Succinate
This product is a key synthetic intermediate of solifenacin succinate [S0944] which is a selective M3 muscarinic receptor antagonist used for the treatment of overactive bladder (OAB).
References
- Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1,2,3,4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists
- One-Pot Racemization Process of 1-Phenyl-1,2,3,4-tetrahydroisoquinoline: A Key Intermediate for the Antimuscarinic Agent Solifenacin
- A validated LC method for the chiral purity of (S)-1,2,3,4-tetrahydro-1-phenylisoquinoline: a key intermediate of solifenacin
Product Documents (Note: Some products will not have analytical charts available.)
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Specifications
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