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Published TCIMAIL newest issue No.197
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CAS RN: 103639-04-9 | Product Number: O0407
Ondansetron Hydrochloride Dihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one Hydrochloride Dihydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€52.00
|
Contact Us | ≥80 |
|
| 5G |
€165.00
|
1 | 28 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | O0407 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__1__9N__3O·HCl·2H__2O = 365.86 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| CAS RN | 103639-04-9 |
| Related CAS RN | 99614-02-5&99614-01-4 |
| Reaxys Registry Number | 7403248 |
| PubChem Substance ID | 172089079 |
| MDL Number | MFCD00374371 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 175.0 to 179.0 °C |
Properties (reference)
| Melting Point | 178 °C |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H301 : Toxic if swallowed. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
Related Laws:
| RTECS# | FE6375500 |
Transport Information:
| UN Number | UN2811 |
| Class | 6.1 |
| Packing Group | III |
| HS Number | 2933299090 |
Application
5-HT3 Receptor Antagonist
References
- The 5-HT3B subunit is a major determinant of serotonin-receptor function
- P. A. Davies, M. Pistis, M. C. Hanna, J. A. Peters, J. J. Lambert, T. G. Hales, E. F. Kirkness, Nature 1999, 397, 359.
- Pharmacological properties of GR38032F, a novel antagonist at 5-HT3 receptors
- The effects of ondansetron (GR38032F) in rats and mice treated subchronically with diazepam
- Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models
- Ondansetron: A review of its pharmacology and preliminary clinical findings in novel applications
- M. I. Wilde, A. Markham, Drugs 1996, 52, 773.
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