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CAS RN: 550-33-4 | Product Number: N1240
Nebularine
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Purity: >95.0%(T)(HPLC)
Synonyms:
- 9-β-D-Ribofuranosyl-9H-purine
- (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
€70.00
|
Contact Us | 5 |
|
| 100MG |
€200.00
|
Contact Us | 26 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | N1240 |
| Purity / Analysis Method | >95.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2N__4O__4 = 252.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 550-33-4 |
| Reaxys Registry Number | 91539 |
| MDL Number | MFCD00022819 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Nonaqueous Titration) | min. 95.0 % |
| Specific rotation | -44.0 to -48.0 deg(C=1, water) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 178 °C |
GHS
Related Laws:
| EC Number | 208-981-9 |
| RTECS# | UO9100000 |
Transport Information:
Application
Nebularine: A Cytotoxic Adenosine Analog with Diverse Biological Activities
Nebularine is a cytotoxic adenosine analog found in the fungus L. nebularis and has diverse biological activities. It has been used as an antineoplastic agent as well as a competitive inhibitor of enzymes, such as adenine deaminase. (The product is for research use only.)
References
- Therapy of mouse leukemia L1210 with combinations of nebularine and nitrobenzylthioinosine 5'-monophosphate
- Plant cytotoxicity of nebularine (purine riboside)
- Nebularine (9-2'-deoxy-β-D-ribofuranosylpurine) has the template characteristics of adenine in vivo and in vitro
- Preparative purification of adenosine deaminase from human erythrocytes by affinity chromatography
Product Documents (Note: Some products will not have analytical charts available.)
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