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CAS RN: 83919-23-7 | Product Number: M2354
Mometasone Furoate
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Purity: >98.0%(HPLC)
Synonyms:
- (11β,16α)-9,21-Dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€48.00
|
Contact Us | 39 |
|
| 1G |
€157.00
|
1 | 13 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | M2354 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__7H__3__0Cl__2O__6 = 521.43 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 83919-23-7 |
| Reaxys Registry Number | 4340538 |
| PubChem Substance ID | 172088987 |
| Merck Index (14) | 6241 |
| MDL Number | MFCD00866003 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Melting point | 212.0 to 216.0 °C |
| Specific rotation [a]20/D | +48.0 to +52.0 deg(C=0.5、MeOH) |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 214 °C(dec.) |
| Specific Rotation | 50° (C=0.5,MeOH) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H361 : Suspected of damaging fertility or the unborn child. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P405 : Store locked up. |
Related Laws:
| RTECS# | TU3822000 |
Transport Information:
| HS Number | 2937220000 |
Application
Studies on Biological Activity of Mometasone
References
- A review of the pharmacology and pharmacokinetics of inhaled fluticasone propionate and mometasone furoate
- In vitro glucocorticoid receptor binding and transcriptional activation by topically active glucocorticoids
- C. L. Smith, W. Kreutner, Arzneim.-Forsch. 1998, 48, 956.
- The inhibitory effects of topically active glucocorticoids on IL-4, IL-5, and interferon-gamma production by cultured primary CD4+ T cells
- Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis
- Progesterone receptor ligand binding pocket flexibility: crystal structures of norethindrone and mometasone furoate complexes
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