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Published TCIMAIL newest issue No.197
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CAS RN: 36703-88-5 | Product Number: I1037
Inosine Pranobex
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 100MG |
20,00 €
|
1 | 9 |
|
| 1G |
124,00 €
|
Contact Us | 3 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product is a sample for RUO (research use only). Do not use this product for any purpose other than testing and research.
| Product Number | I1037 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__0H__1__2N__4O__5·3C__9H__9NO__3·3C__5H__1__3NO = 1,115.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic |
| CAS RN | 36703-88-5 |
| PubChem Substance ID | 354334341 |
| Merck Index (14) | 4976 |
| MDL Number | MFCD05662374 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -9.0 to -13.0 deg(C=1, H2O) |
Properties (reference)
| Specific Rotation | -11° (C=1,H2O) |
| Solubility (soluble in) | Methanol, Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| EC Number | 253-162-1 |
Transport Information:
| HS Number | 2933998090 |
Application
Inosine Pranobex: An Immunostimulant Agent with Antiviral Activities
Inosine pranobex is a synthetic compound formed from the 4-acetamidobenzoate [A0013] salt of 1-dimethylamino-2-propanol [D0660] and inosine [I0037] in a 3:1 molar ratio. It is an immunostimulant agent that supports the immune system through modulation of T-cell proliferation and T-cell function. In addition, it has been reported to exert antiviral activities in vivo. In 2010, Petrova et al. has reported that inosine pranobex is capable of increasing cytokine levels (IFN-γ, IL-10 and TNF-α) in healthy adults. (The product is for research purpose only.)
References
- Inosine pranobex. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
- Inosine pranobex in the treatment of HIV infection: a review
- Isoprinosine Affects Serum Cytokine Levels in Healthy Adults
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