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CAS RN: 198637-52-4 | Product Number: G0503
Gadobutrol Monohydrate
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Purity: >98.0%(T)
Synonyms:
- Gadolinium(III) 2,2',2''-[10-(1,3,4-Trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetate Monohydrate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 25MG |
74,00 €
|
1 | 20 |
|
| 100MG |
245,00 €
|
1 | ≥40 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | G0503 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__8H__3__1GdN__4O__9·H__2O = 622.74 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Hygroscopic,Heat Sensitive |
| CAS RN | 198637-52-4 |
| Reaxys Registry Number | 15557943 |
| PubChem Substance ID | 468591918 |
| MDL Number | MFCD29917846 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Chelometric Titration) | min. 98.0 % |
| Water | 2.6 to 3.1 % |
Properties (reference)
| Solubility (insoluble in) | Ethanol |
GHS
Related Laws:
Transport Information:
| HS Number | 2846906015 |
Application
Gadobutrol: A Paramagnetic Macrocyclic Contrast Agent for MRI
Gadobutrol, gadolinium complex, is a paramagnetic macrocyclic contrast agent used for magnetic resonance imaging (MRI). Contrast-enhanced MRI has become a mainstay of imaging with unlimited applications. In a magnetic field, gadobutrol shortens the T1 (spin-lattice or longitudinal) relaxation times, which improves MR image quality. Gadobutrol is often used as an aqueous solution (1 mmol/mL) mixed with calcobutrol sodium, tris(hydroxymethyl)aminomethane (another name: trometamol) and hydrochloric acid (for pH adjustment). (The product is for research purpose only.)
References
- Longitudinal assessment of blood-brain barrier leakage during epileptogenesis in rats. A quantitative MRI study
- Signal Increase on Unenhanced T1-Weighted Images in the Rat Brain after Repeated, Extended Doses of Gadolinium-Based Contrast Agents: Comparison of Linear and Macrocyclic Agents
- Gadobutrol: A Review of Its Use for Contrast-Enhanced Magnetic Resonance Imaging in Adults and Children (a review)
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