Maintenance Notice (4:30 AM - 11:00 AM December 21, 2024): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Published TCIMAIL newest issue No.197
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 76095-16-4 | Product Number: E1010
Enalapril Maleate
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-[N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-L-proline Maleate
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€40.00
|
1 | 23 |
|
| 5G |
€133.00
|
Contact Us | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | E1010 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__2__8N__2O__5·C__4H__4O__4 = 492.53 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 76095-16-4 |
| Related CAS RN | 75847-73-3 |
| Reaxys Registry Number | 3645274 |
| PubChem Substance ID | 253661645 |
| Merck Index (14) | 3567 |
| MDL Number | MFCD00133304 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -40.0 to -43.0 deg(C=1, MeOH) |
Properties (reference)
| Melting Point | 144 °C(dec.) |
| Specific Rotation | -41° (C=1,MeOH) |
| Maximum Absorption Wavelength | 208(MeOH) nm |
| Solubility in water | Slightly soluble |
| Degree of solubility in water | 25 g/l 25 °C |
| Solubility (soluble in) | Ethanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| EC Number | 278-375-7 |
| RTECS# | TW3666000 |
Transport Information:
| HS Number | 2933998090 |
Application
Enalapril Maleate: An Angiotensin-Converting Enzyme Inhibitor (ACEI)
Enalapril maleate is an angiotensin-converting enzyme inhibitor (ACEI) without a mercapto group, used in the treatment of hypertension. Enalapril is a prodrug which is hydrolysed by various esterases in the host's liver to form the ACEI, enalaprilat [E1302]. Enalapril increases plasma renin activity (PRA) and decreases plasma concentrations of angiotensin II and aldosterone. (The product is for research purpose only.)
References
- Enalapril maleate (MK-421), a potent, nonsulfhydryl angiotensin-converting enzyme inhibitor: absorption, disposition, and metabolism in man (a review)
- Enalapril. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and congestive heart failure (a review)
- Enalapril maleate (a review)
- Enalapril: pharmacokinetic/dynamic inferences for comparative developmental toxicity (a review)
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.