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CAS RN: 660-27-5 | Product Number: D5074
Diisopropylamine Dichloroacetate
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Purity: >98.0%(T)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
€56.00
|
2 | ≥40 |
|
| 5G |
€187.00
|
1 | ≥100 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | D5074 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__6H__1__5N·C__2H__2Cl__2O__2 = 230.13 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 660-27-5 |
| Reaxys Registry Number | 4158968 |
| PubChem Substance ID | 354333577 |
| Merck Index (14) | 3197 |
| MDL Number | MFCD00868288 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 120.0 to 124.0 °C |
Properties (reference)
| Melting Point | 122 °C |
| Solubility (soluble in) | Methanol |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H302 : Harmful if swallowed. H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth. |
Related Laws:
| EC Number | 211-538-2 |
| RTECS# | AG6475000 |
Transport Information:
| HS Number | 2921199990 |
Application
Diisopropylamine Dichloroacetate: An Active Component of Pangamic Acid (Once Called "Vitamin B15")
Diisopropylamine dichloroacetate (abbrev.: DADA or DIPA) is an active component of pangamic acid (once called "vitamin B15") which was first isolated from apricot seeds by Krebs et al. in 1951. In 1958, Casu et al. revealed that pangamic acid is a mixture of DADA, sodium gluconate [G0041] and glycine [G0099]. And then, DADA has received attention for its pharmacologic and therapeutic effects, especially on hepatic function. (The product is for research purpose only.)
References
- Pangamic acid sodium: a newly isolated crystalline water-soluble factor; a preliminary report.
- Analysis of commercial samples of vitamin B15
- Review of the pharmacologic and therapeutic effects of diisopropylammonium dichloroacetate (DIPA) (a review)
- Diisopropylammonium dichloroacetate (DIPA) and sodium dichloroacetate (DCA): Effect on glucose and fat metabolism in normal and diabetic tissue
- Pangamic acid vitamin B15 (a review)
- Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza
PubMed Literature
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