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Published TCIMAIL newest issue No.197
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CAS RN: 117467-28-4 | Product Number: C2856
Cefditoren Pivoxil
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
€165.00
|
1 | 26 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2856 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__2__8N__6O__7S__3 = 620.71 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 117467-28-4 |
| Reaxys Registry Number | 4902739 |
| PubChem Substance ID | 253661532 |
| Merck Index (14) | 1921 |
| MDL Number | MFCD00933166 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Specific rotation [a]20/D | -45.0 to -52.0 deg(C=0.5, MeOH) |
| Water | max. 1.5 % |
Properties (reference)
| Melting Point | 209 °C(dec.) |
| Specific Rotation | -48.5° (C=0.5,MeOH) |
| Solubility in water | Insoluble |
| Solubility (slightly sol. in) | Methanol |
| Solubility (insoluble in) | Ether |
GHS
Related Laws:
| RTECS# | XI0367800 |
Transport Information:
| HS Number | 2933998090 |
Application
Cefditoren pivoxil: A Third-Generation Cephalosporin with Antibacterial Effects against PRSP and BLNAR
Cefditoren pivoxil is a prodrug of the third-generation cephalosporin that is rapidly hydrolyzed by intestinal esterases to the microbiologically active cephalosporin cefditoren. Cefditoren has broad spectrum of activity against Gram-positive and Gram-negative bacteria, including common respiratory and skin pathogens. Cefditoren has potent antibacterial effects against penicillin-resistant Streptococcus pneumoniae (PRSP) and β-lactamase-non-producing-ampicillin resistant (BLNAR) Haemophilus influenzae among the oral β-lactam antibiotics. However, cefditoren does not have antibacterial activity against Pseudomonas aeruginosa.For your reference, [M2411] is a synthetic intermediates of cefditoren pivoxil. (The product is for research purpose only.)
References
- Antimicrobial activity and in vitro susceptibility test development for cefditoren against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus species
- Crystal structure of cefditoren complexed with Streptococcus pneumoniae penicillin-binding protein 2X: structural basis for its high antimicrobial activity
- Cefditoren pivoxil (a review)
- Cefditoren pivoxil: A review of its use in the treatment of bacterial infections
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