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Published TCIMAIL newest issue No.197
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CAS RN: 1426397-23-0 | Product Number: C2598
Cefsulodin Sodium Salt Hydrate
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Purity: >95.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 200MG |
63,00 €
|
1 | 11 |
|
| 1G |
244,00 €
|
1 | 4 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
This product has not been tested for potency and is guaranteed for chemical purity.
| Product Number | C2598 |
| Purity / Analysis Method | >95.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__2H__1__9N__4NaO__8S__2·xH__2O = 554.52 (as Anhydrous) |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Moisture Sensitive,Hygroscopic,Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image), 200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 1426397-23-0 |
| Related CAS RN | 62587-73-9&52152-93-9 |
| Reaxys Registry Number | 5403947 |
| PubChem Substance ID | 135727259 |
| Merck Index (14) | 1945 |
Specifications
| Appearance | White to Yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(with Total Nitrogen) | min. 95.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | +16.0 to +20.0 deg(C=1, H2O)(calcd.on anh.substance) |
| Water | max. 10.0 % |
| NMR | confirm to structure |
Properties (reference)
| Specific Rotation | 19° (C=1,H2O) |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. |
| Precautionary Statements | P261 : Avoid breathing dust. P280 : Wear protective gloves. P284 : Wear respiratory protection. P342 + P311 : If experiencing respiratory symptoms: Call a POISON CENTER/doctor. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
| EC Number | 257-692-4 |
| RTECS# | UU1785000 |
Transport Information:
| HS Number | 2941900000 |
Application
Cefsulodin Sodium Salt: A Third Generation Cephalosporin Antibiotic with Specific Activity against Pseudomonas Aeruginosa
Cefsulodin sodium salt is a third generation semisynthetic cephalosporin antibiotic, which is chemically synthesized form 7-aminocephalosporanic acid (7-ACA) [A1266]. It has a narrow-spectrum restricted to Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. It has increased stability to β-lactamases like the other third generation cephalosporin antibiotics.
References
- In vitro antibacterial activity and susceptibility of cefsulodin, an antipseudomonal cephalosporin, to beta-lactamases
- The penetration of antibiotics into aggregates of mucoid and non-mucoid Pseudomonas aeruginosa
- Cross-resistance to meropenem, cephems, and quinolones in Pseudomonas aeruginosa
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