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Published TCIMAIL newest issue No.197
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CAS RN: 284462-37-9 | Product Number: A2617
4-(4-Aminophenoxy)-N-methyl-2-pyridinecarboxamide
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Purity: >98.0%(T)(HPLC)
Synonyms:
- 4-(4-Aminophenoxy)-N-methylpicolinamide
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 1G |
29,00 €
|
2 | 19 |
|
| 5G |
93,00 €
|
1 | 2 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
| Product Number | A2617 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__1__3N__3O__2 = 243.27 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 284462-37-9 |
| Reaxys Registry Number | 11461032 |
| PubChem Substance ID | 253659779 |
| MDL Number | MFCD08692047 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystalline |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Nonaqueous Titration) | min. 98.0 % |
| Melting point | 116.0 to 120.0 °C |
Properties (reference)
| Melting Point | 118 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| HS Number | 2933399990 |
Application
A Synthetic Intermediate of Sorafenib and Its Structural Analogs
This product has been used as a synthetic intermediate of protein kinase inhibitors, such as an antitumor sorafenib (BAY 43-9006) [O0599] and its structural analogs.
References
- A Scaleable Synthesis of BAY 43-9006: A Potent Raf Kinase Inhibitor for the Treatment of Cancer
- Convenient synthesis of Sorafenib and its derivatives
- Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents
- Design, synthesis, activity and docking study of sorafenib analogs bearing sulfonylurea unit
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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