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Published TCIMAIL newest issue No.197
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CAS RN: 2016-88-8 | Product Number: A2599
Amiloride Hydrochloride
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Purity: >98.0%(HPLC)(N)
Synonyms:
- N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide Hydrochloride
- 3,5-Diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide Hydrochloride
Product Documents:
| Size | Unit Price | Belgium | Japan* | Quantity |
|---|---|---|---|---|
| 5G |
40,00 €
|
3 | 30 |
|
*Stock available in Belgium will be delivered in 1 to 3 days
*Stock available in Japan will be delivered in 1 to 2 weeks (excludes regulated items and dry ice shipments).
Supplemental Product Information:
Previously this product had been labeled as a hydrate form both in product name and molecular formula. The hydrate form had no exclusive CAS RN and used to share the same CAS RN as the anhydrous form.
To avoid any misleading information and since moisture in product is considered as an impurity, we have decided to remove the term 'Hydrate' from product name and 'xH2O' from the molecular formula for such products.
Please use it at ease since there is no difference in product quality, even if you see the previous indications on a part of label.
| Product Number | A2599 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__6H__8ClN__7O·HCl = 266.09 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 2016-88-8 |
| Related CAS RN | 2609-46-3 |
| Reaxys Registry Number | 4038903 |
| PubChem Substance ID | 253660013 |
| MDL Number | MFCD00058197 |
Specifications
| Appearance | Light yellow to Yellow to Green powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 %(calcd.on anh.substance) |
| Water | 8.0 to 15.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 299 °C |
GHS
Related Laws:
| EC Number | 217-958-2 |
| RTECS# | UQ2275500 |
Transport Information:
| HS Number | 2933998090 |
Application
Extracellular vesicle research / Exosome research
References
- Selective transfer of exosomes from oligodendrocytes to microglia by macropinocytosis
- Amiloride ameliorates muscle wasting in cancer cachexia through inhibiting tumor-derived exosome release
Application
Studies of Amiloride-Sensitive Epithelial Na+ Channels
References
- Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits
- Structure and function of amiloride-sensitive Na+ channels
- Amiloride-sensitive Na channels
- Role of the amiloride-sensitive epithelial Na+ channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease
Application
Studies of Anti-tumor/metastasis effects of amiloride
References
- Anti-tumor/metastasis effects of the potassium-sparing diuretic amiloride: An orally active anti-cancer drug waiting for its call-of-duty?
PubMed Literature
Articles/Brochures
TCIMAIL
Product Documents (Note: Some products will not have analytical charts available.)
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