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CAS RN: 2315-02-8 | Product Number: O0520
Oxymetazoline Hydrochloride
Purity: >98.0%(T)(HPLC)
Synonyms:
- 2-(3-Hydroxy-2,6-dimethyl-4-tert-butylbenzyl)-2-imidazoline Hydrochloride
Product Documents:
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Product Number | O0520 |
Purity / Analysis Method | >98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__1__6H__2__4N__2O·HCl = 296.84 |
Physical State (20 deg.C) | Solid |
Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
CAS RN | 2315-02-8 |
Related CAS RN | 1491-59-4 |
Reaxys Registry Number | 5462995 |
PubChem Substance ID | 468592536 |
Merck Index (14) | 6966 |
MDL Number | MFCD00058147 |
Specifications
Appearance | White to Light yellow powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
Properties (reference)
Melting Point | 303 °C |
Solubility (soluble in) | Ethanol |
Solubility (insoluble in) | Diethyl ether, Benzene, Chloroform, Ether |
GHS
Pictogram | |
Signal Word | Danger |
Hazard Statements | H300 + H330 : Fatal if swallowed or if inhaled. H318 : Causes serious eye damage. H412 : Harmful to aquatic life with long lasting effects. |
Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P270 : Do not eat, drink or smoke when using this product. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear eye protection/ face protection. P284 : Wear respiratory protection. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
Related Laws:
RTECS# | SK1225000 |
Transport Information:
UN Number | UN2811 |
Class | 6.1 |
Packing Group | I |
H.S.code* | 2933.29-000 |
Application
Oxymetazoline Hydrochloride: An Imidazoline α-Adrenoceptor Agonist.
Oxymetazoline hydrochloride is an imidazoline α-adrenoceptor agonist. It reportedly elicits vasoconstriction of dilated arterioles and reduces nasal blood flow. (The product is for research purpose only.)
References
- Comparative pharmacodynamics of sympathomimetic imidazolines; studies on intestinal smooth muscle of the rabbit and the cardiovascular system of the cat
- Characterization of α-adrenoceptors in the vasculature of the canine nasal mucosa
- Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes
- Rapid liquid chromatographic-mass spectrometric assay for oxymetazoline in whole rat blood
- Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC
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