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CAS RN: 152121-30-7 | Product Number: F0870
SB 202190
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Purity: >95.0%(HPLC)
Synonyms:
- 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
- 4-[4-(4-Fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
- 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
$219.00
|
15 | 0 | Contact Us |
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| Product Number | F0870 |
| Purity / Analysis Method | >95.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__0H__1__4FN__3O = 331.35 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 152121-30-7 |
| Reaxys Registry Number | 7654810 |
| MDL Number | MFCD00941964 |
Specifications
| Appearance | White to Light yellow to Light orange powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 215 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | SL4584000 |
Transport Information:
| H.S.code* | 2933.39-000 |
Application
SB 202190: A Selective Inhibitor of p38 MAPK
SB 202190 is a selective inhibitor of p38 MAP kinase (mitogen-activated protein kinase, MAPK), a serine/threonine-specific protein kinase. SB 202190 has been reported to induce apoptosis. (The product is for research purpose only.)
References
- Characterization of the structure and function of a new mitogen-activated protein kinase (p38β)
- Specificity and mechanism of action of some commonly used protein kinase inhibitors
- Induction of apoptosis by SB202190 through inhibition of p38β mitogen-activated protein kinase
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